A new study from researchers at the IRCM sheds light on a mechanism affecting AID, a crucial enzyme for the immune response. The scientific breakthrough could eventually improve the way researchers treat the common flu, as well as lymphoma and leukemia.
The researchers study white blood cells, called B-lymphocytes, whose main function is to produce antibodies to fight against infections. More specifically, they focus on an enzyme found in B cells known as AID, or activation-induced deaminase. The team explain that AID is crucial for an efficient antibody response. However, high levels of AID can also have harmful effects and lead to certain cancer-causing mutations. The objective is to find the perfect level of AID activity to maximise the protection it provides to the body while reducing the risk of damage it can cause to cells.
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